INTERNIST · THESSALONIKI, GREECE

Dr. Despoina Rizopoulou

Internal Medicine · Medical Acupuncture · Longevity Care

Medicine is not only the treatment of illness. It is understanding the person behind the symptoms — and guiding them towards a healthier, more complete life.

EXPERIENCE
20+
Years of clinical practice
PATIENT SATISFACTION
10 /10
doctoranytime.gr
SPECIALTIES
2
Pathology + Acupuncture
Clinical Profile
20+
Years of clinical practice
Patient Satisfaction
10/10
doctoranytime.gr
Focused Areas
Internal Medicine Medical Acupuncture Longevity Care
Credentials
Research International Clinical Studies — Diabetes & Oncology
Publications Greek & International Medical Journals
Degree Medical School of the University of Thessaly, 1997
Specialty Pathology — Hippocrates of Thessaloniki, 2006
Member ESPEN — European Society for Clinical Nutrition & Metabolism
Certification ALS Provider — Advanced Life Support, 2014
Education Medical Acupuncture — IABIE of Northern Greece
Clinic EUROMEDICA — Pathological Oncology, 2015–2022
Research International Clinical Studies — Diabetes & Oncology
Publications Greek & International Medical Journals
Degree Medical School of the University of Thessaly, 1997
Specialty Pathology — Hippocrates of Thessaloniki, 2006
Member ESPEN — European Society for Clinical Nutrition & Metabolism
Certification ALS Provider — Advanced Life Support, 2014
Education Medical Acupuncture — IABIE of Northern Greece
Clinic EUROMEDICA — Pathological Oncology, 2015–2022
A NOTE FROM THE DOCTOR

A few words, without the medical jargon

PHYSICIAN
Dr. Despina Rizopoulou — Specialist Pathologist
PRACTICES
Thermi · Kalamaria · Thessaloniki

In the years I have been practicing medicine, I have seen thousands of people arrive with conditions that should never have progressed this far. Blood pressure that had been high for years, blood sugar quietly rising, fatigue attributed to "stress" that was never properly investigated.

My job is not to tell you what you're doing wrong. It is to help you understand what is happening in your body — and together find a realistic, sustainable way to change it. Without extremes, without judgement.

Alongside internal medicine, I practice medical acupuncture — an evidence-based approach I use as a complement to conventional medicine, whenever each patient needs it.

AREAS OF CARE

What brings you here today?

Select the area that concerns you most to see my clinical approach.

🫀

Cardiovascular Health

HYPERTENSION · CHOLESTEROL · RISK
CLINICAL PRIORITY
High
LONG-TERM MONITORING
Required
EVIDENCE BASE
Strong — ESC/ESH Guidelines 2023
CLINICAL ASSESSMENT

Hypertension doesn't hurt — until it's too late.

Arterial hypertension is called the "silent killer" for good reason. In the vast majority of cases it produces no symptoms until a cardiovascular event occurs. It is effectively managed — provided it is identified early and monitored systematically.

CLINICAL APPROACH
  • Total cardiovascular risk assessment (SCORE2) based on age, sex and risk factors
  • Optimization of pharmacotherapy combined with lifestyle modification
  • Regular monitoring with individualized target levels per patient
Book an appointment
🩸

Diabetes Mellitus

TYPE 2 · INSULIN RESISTANCE · HBA1C
CLINICAL PRIORITY
High
REVERSIBILITY (TYPE 2)
Achievable with intervention
EVIDENCE BASE
Strong — ADA Standards of Care 2024
CLINICAL ASSESSMENT

Type 2 diabetes is not fate. In many cases, it is preventable.

I specialize in diabetes and have participated as a researcher in international clinical studies on the disease. Its management goes beyond pharmacotherapy — it requires a holistic approach covering nutrition, weight, physical activity and psychological support.

CLINICAL APPROACH
  • Full metabolic assessment: HbA1c, fasting glucose, insulin, lipids, renal function
  • Individualized glycemic targets based on age, comorbidities and quality of life
  • Lifestyle intervention as first-line treatment for pre-diabetes
Book an appointment
⚖️

Body Weight & Metabolism

METABOLIC SYNDROME · OBESITY · HEALTH
CLINICAL BASIS
Medical indication, not aesthetics
BMI RISK THRESHOLD
≥ 25 kg/m² (regardless of appearance)
EVIDENCE BASE
Strong — WHO / ESO Guidelines
CLINICAL ASSESSMENT

Weight management is a medical matter — not a question of appearance or willpower.

I discuss weight with my patients because its impact on chronic disease is among the best documented in medicine. Obesity increases the risk of type 2 diabetes 7-fold, hypertension 5-fold, cardiovascular disease 3-fold. My approach is strictly biomedical — no judgment, no extremes.

CLINICAL APPROACH
  • Metabolic assessment: thyroid, insulin, cortisol, inflammation markers
  • Personalized plan without restrictive diets — sustainable long-term changes
  • Medical acupuncture as a complement for appetite regulation and stress reduction
Book an appointment
😴

Stress, Sleep & Nervous System

CORTISOL · HRV · AUTONOMIC BALANCE
BIOLOGICAL IMPACT
Accelerates cellular aging
EVIDENCE BASE
Good — Multiple meta-analyses
CLINICAL ASSESSMENT

Chronic stress is not "just psychological" — it leaves measurable traces in the body.

Chronic insomnia and stress are linked to elevated cortisol, immune dysregulation, accelerated atherosclerotic disease and increased risk of metabolic syndrome. I address these conditions in combination — with clinical assessment, pharmacological intervention when necessary, and medical acupuncture.

CLINICAL APPROACH
  • Tests: cortisol, thyroid, vitamin D, iron — exclusion of organic cause
  • Medical acupuncture for autonomic nervous system regulation — evidenced protocol
  • Pharmacological sleep support only when clinically justified, short-term
Book an appointment
🔬

Preventive Screening

PERSONALIZED PROTOCOL
IDEAL FREQUENCY
Annual (regardless of symptoms)
EVIDENCE BASE
Strong — USPSTF · ESC Prevention Guidelines
CLINICAL ASSESSMENT

Most serious diseases have a silent phase. That is where we can make a difference.

Preventive screening is not a fixed "package of tests". It is an individualized strategy based on age, family history, lifestyle and risk factors. A result that appears "normal" may not be optimal for the specific patient.

CLINICAL APPROACH
  • Analysis of family history and genetic risk factors
  • Personalized protocol: haematological, cardiovascular, oncological, metabolic screening
  • Interpretation in the context of the specific patient — not simply comparison to "normal ranges"
Book an appointment
🚭

Smoking Cessation

DEPENDENCE · WITHDRAWAL · LONGEVITY
LIFE EXPECTANCY GAIN
+10 years (age 40)
EVIDENCE BASE
Strongest — The #1 longevity intervention
CLINICAL ASSESSMENT

Smoking cessation is the highest-return investment in longevity medicine.

Nicotine dependence is a neurobiological disease — not a character weakness. Its treatment requires a combination of pharmacotherapy, behavioral support and, in many cases, medical acupuncture for withdrawal anxiety management.

CLINICAL APPROACH
  • Dependence level assessment (Fagerström score) and motivation evaluation
  • Pharmacological protocol: varenicline or NRT based on clinical picture
  • Medical acupuncture for withdrawal anxiety reduction — 6–8 session protocol
Book an appointment
AREAS OF CARE

What brings you here today?

Select the area that concerns you most to see my clinical approach.

🫀

Arterial Hypertension

blood pressure · vascular health · monitoring
Clinical Priority

High

Monitoring Focus

Regular follow-up and individualized targets

Evidence Base

Strong — guideline-based cardiovascular prevention

Clinical Assessment

Arterial hypertension often stays silent until damage has already begun.

This section is positioned around structured blood pressure assessment, cardiovascular risk evaluation, and long-term monitoring. The clinical approach should present hypertension as a measurable risk state, not just a symptom-driven complaint.

Clinical Approach

  • Blood pressure assessment with individualized cardiovascular risk review
  • Evaluation of associated risk factors and target-organ implications
  • Lifestyle, follow-up strategy, and treatment optimization based on the patient profile
Book an appointment
🩺

Hyperlipidemia / Cardiovascular Risk

cholesterol · lipids · prevention
Clinical Priority

High

Risk Focus

Primary and secondary prevention planning

Evidence Base

Strong — lipid management and cardiovascular risk reduction

Clinical Assessment

Lipid disorders should be approached as part of total cardiovascular risk — not in isolation.

This area should clearly frame hyperlipidemia together with cardiovascular prevention. It should help the patient understand that cholesterol values matter most in the context of overall vascular risk, family history, and coexisting metabolic factors.

Clinical Approach

  • Interpretation of lipid profile in a full cardiovascular-risk context
  • Risk-factor review including family history, blood pressure, metabolic profile, and lifestyle
  • Prevention strategy tailored to long-term risk reduction
Book an appointment
🩸

Insulin Resistance

prediabetes · glucose metabolism · early risk
Clinical Priority

High

Continuum

Insulin resistance → prediabetes → type 2 diabetes

Evidence Base

Strong — early metabolic assessment matters

Clinical Assessment

Insulin resistance is often the earlier metabolic signal — before type 2 diabetes is established.

The page should be framed as a metabolic continuum, not only for patients with established diabetes. This makes the section broader, more clinically precise, and more relevant to early intervention.

Clinical Approach

  • Assessment of fasting glucose, HbA1c, insulin, and metabolic profile
  • Identification of early-stage dysregulation before advanced disease
  • Prevention-focused management aimed at improving long-term metabolic outcomes
Book an appointment
⚖️

Weight / Metabolic Syndrome

waist circumference · fatty liver · blood pressure
Clinical Frame

Metabolic risk, not aesthetics

Assessment Focus

Weight is reviewed in a wider metabolic context

Evidence Base

Strong — obesity and metabolic syndrome management

Clinical Assessment

Insulin resistance, excess weight, and metabolic risk belong in the same clinical discussion.

The updated section should move away from generic wellness language and place body weight inside a proper metabolic evaluation framework, including waist circumference, fasting insulin / HOMA-IR, HbA1c, lipids, fatty liver, and blood pressure.

Clinical Approach

  • Assessment of weight in the context of metabolic syndrome and cardiometabolic risk
  • Review of insulin resistance markers, lipid profile, and liver-related metabolic indicators
  • Individualized plan based on clinical findings rather than appearance-driven goals
Book an appointment
😴

Sleep / Stress / Autonomic Nervous System

cortisol · regulation · cardiometabolic effects
Clinical Angle

Stress physiology and autonomic regulation

Support Focus

Sleep quality, sympathetic load, recovery balance

Evidence Base

Good — sleep and autonomic dysregulation assessment

Clinical Assessment

Stress and poor sleep are not just psychological — they can leave measurable biological effects.

This section should use clinically precise terminology by naming the autonomic nervous system directly and linking sleep/stress with sympathetic-parasympathetic regulation, cortisol balance, and cardiometabolic consequences.

Clinical Approach

  • Clinical review of sleep pattern, stress physiology, and autonomic regulation
  • Discussion of cortisol, recovery balance, and downstream metabolic effects
  • Individualized support based on the patient’s symptom pattern and medical context
Book an appointment
🔬

Prevention / Check-up / Vaccinations / Infections

screening · prevention · individualized follow-up
Screening Logic

Frequency should be individualized

Clinical Scope

Check-up strategy, risk review, prevention planning

Evidence Base

Strong — risk-based preventive medicine

Clinical Assessment

Most serious conditions have a silent phase — prevention works best before symptoms become obvious.

This section should group check-up logic, vaccinations, infections, and preventive screening into one clear preventive cluster. It should also avoid rigid wording such as annual screening for everyone and instead emphasize individualized frequency.

Clinical Approach

  • Preventive planning based on age, sex, family history, risk factors, and prior findings
  • Structured check-up and screening interpretation in a patient-specific context
  • Preventive counseling including vaccination and infection-related guidance where relevant
Book an appointment
🚭

Smoking Cessation

dependence · withdrawal · support
Clinical Priority

High-impact preventive intervention

Support Focus

Withdrawal-symptom management and autonomic regulation

Evidence Base

Strongest — one of the most meaningful long-term health interventions

Clinical Assessment

Smoking cessation remains one of the highest-value interventions in long-term preventive medicine.

Nicotine dependence should be presented with clear clinical language, without sounding moralistic. Medical acupuncture should not be limited to withdrawal anxiety only. It is better framed as complementary support for autonomic nervous system regulation and withdrawal-symptom management.

Clinical Approach

  • Assessment of dependence severity, readiness, and prior quit attempts
  • Pharmacologic and behavioral support based on real clinical practice
  • Medical acupuncture as complementary support for autonomic regulation and withdrawal symptoms
Book an appointment
METABOLISM & BODY WEIGHT

Healthy weight is a medical matter

I speak regularly with my patients about weight — not for aesthetic reasons, but because its relationship with chronic disease is scientifically indisputable. Our goal is always your health, never a number on a scale.

Metabolic syndrome: Hypertension + blood sugar + weight + lipids — treated holistically as one entity.

No extreme diets: Only sustainable changes the body can maintain long-term.

Acupuncture as support: Appetite and metabolic regulation — scientifically studied.

CLINICAL METABOLIC RISK INDICATOR
Optimal
Optimal Pre-risk Risk
Drag to explore the intervention zone at each risk level
01

Metabolic Stability

Current indicators suggest a balanced metabolic profile. Focus remains on prevention, healthy nutrition, movement consistency, and maintaining insulin sensitivity over time.

02

Lifestyle Precision

At this stage, small structured adjustments usually create the biggest long-term benefit. Sleep, meal timing, and inflammation control matter more than aggressive dieting.

03

Preventive Monitoring

Periodic laboratory review and body composition follow-up help preserve a low-risk trajectory before silent metabolic drift begins.

MEDICAL ACUPUNCTURE

Evidence-based clinical application

Medical acupuncture is not alternative — it is complementary. It is applied with medical indications and an evidence base. Below you see the main applications and the strength of evidence for each.

ANATOMICAL APPLICATION ZONES
Head
Chest
Abdomen
Lower limbs
🧠 Headaches & Migraines
Grade A

The effectiveness of acupuncture for chronic tension-type headaches and migraines is well documented by multiple RCTs and meta-analyses. The 2022 Cochrane Review confirms equivalent effectiveness with pharmacological prophylaxis.

Source: Cochrane Review 2022 · Linde et al. · Grade A Evidence

🦴 Chronic Pain — Back & Neck
Grade A
😰 Anxiety & Insomnia
Grade B
⚖️ Weight Management Support
Grade B
🚭 Smoking Cessation — Withdrawal Anxiety
Grade B
🌡️ Electroacupuncture — Musculoskeletal Pain
Grade A
EVIDENCE GRADE: Grade A Strong RCTs · meta-analyses Grade B
Good evidence · growing body of data
PATIENT REVIEW

Trust
is not stated — it is earned.

“Excellent doctor with deep knowledge and great care for patients.”

D
Dimitris ✔ Verified visit
10 / 10

"An outstanding physician and, above all, a remarkable human being. With a high level of scientific knowledge, attention to detail and genuine care for the patient, she inspires absolute trust."

Scientific Level 10
Trust 10
Thoroughness 10
Reliability 10
Manner 10

“Very professional, kind, and highly recommended.”

CONTACT

The first step :
a simple question.

"What would you like to change about your health?" Every first appointment begins with this question. Book online or by phone.

CLINIC 1 THERMI

Nea Raidesto Private Practice

Polytechneiou 33 · Nea Radestos, Thermi
CLINIC 2 · KALAMARIA

Iatropolis —
Kalamaria Polyclinic

Adrianoupoleos 34 & Karolidis P. 31 · Kalamaria
📞 2310 438300
ONLINE APPOINTMENT

Video consultation via doctoranytime

Available for patients outside Thessaloniki
STRATEGIC FOUNDATION · DOCUMENTATION

This website is underpinned by a comprehensive 12-page brand strategy report

Consultant: Vasilios G Kotitsas · vk@UberConsul.com · Publicis Groupe Methodology · Zero Hallucination Protocol · GDPR (EU 2016/679) & HIPAA Compliant · March 2026
23 verified clinical references: ESC · ADA · WHO · Cochrane Reviews · ESPEN · USPSTF